Effects of estradiol and progestogens on human breast cells: Regulation of sex steroid receptors

Effects of estradiol and progestogens on human breast cells: Regulation of sex steroid receptors

Objectives: To examine the effects of 17β-estradiol (E2) and progestogens, used in hormone therapy, on estrogen receptors (ER), progesterone receptors (PR), and human breast tumor cell growth. Materials and methods: MCF-7 cells were incubated in pure E2 (1 nM and 10 nM) as well as in E2 in conjuncti...

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Bibliographic Details
Main Authors: Fang-Ping Chen, Mei-Hua Chien, Huang-Yang Chen, Ting-Shuo Huang, Yuet-Tong Ng
Format: Article
Language:English
Published: Elsevier 2013-09-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
17-β-estradiol
caspase-3
estrogen receptor
progesterone receptor
progestogen
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455913001198

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http://www.sciencedirect.com/science/article/pii/S1028455913001198

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