Development of a sandwich ELISA to detect Leishmania 40S ribosomal protein S12 antigen from blood samples of visceral leishmaniasis patients

Development of a sandwich ELISA to detect Leishmania 40S ribosomal protein S12 antigen from blood samples of visceral leishmaniasis patients

Abstract Background Visceral leishmaniasis (VL), caused by Leishmania donovani complex parasites, is a neglected parasitic disease that is generally fatal if untreated. Despite decades of research to develop a sensitive VL diagnostic test, definitive diagnosis of VL still mainly relies on the visual...

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Bibliographic Details
Main Authors: Wen-Wei Zhang, Ayan Kumar Ghosh, Raodoh Mohamath, Jacqueline Whittle, Alessandro Picone, Patrick Lypaczewski, Momar Ndao, Randall F Howard, Pradeep Das, Steven G Reed, Greg Matlashewski
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Infectious Diseases
Subjects:
Visceral Leishmaniasis
Diagnosis
ELISA
PBMC
40S ribosomal protein S12
Online Access:http://link.springer.com/article/10.1186/s12879-018-3420-2

Internet

http://link.springer.com/article/10.1186/s12879-018-3420-2

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