Crosstalk of the insulin-like growth factor receptor with the Wnt signaling pathway in breast cancer
The insulin-like growth factor system has long been considered a pathway that promotes cell proliferation, survival and transformation and is thus a promoter of tumorigenesis. However, recent failure of clinical trials for IGF-1R inhibitors reveals the need for a better understanding of how this pat...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2015-06-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00092/full |