Matrix metalloproteinase 7 is associated with symptomatic lesions and adverse events in patients with carotid atherosclerosis.

BACKGROUND: Atherosclerosis is a major cause of cerebrovascular disease. Matrix metalloproteinases (MMPs) play an important role in matrix degradation within the atherosclerotic lesion leading to plaque destabilization and ischemic stroke. We hypothesized that MMP-7 could be involved in this process...

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Bibliographic Details
Main Authors: Azhar Abbas, Pål Aukrust, David Russell, Kirsten Krohg-Sørensen, Trine Almås, Dorte Bundgaard, Vigdis Bjerkeli, Ellen Lund Sagen, Annika E Michelsen, Tuva B Dahl, Sverre Holm, Thor Ueland, Mona Skjelland, Bente Halvorsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3882279?pdf=render