Are immune-related adverse events associated with the efficacy of immune checkpoint inhibitors in patients with cancer? A systematic review and meta-analysis

Abstract Background A number of studies have reported an association between the occurrence of immune-related adverse events (irAEs) and clinical efficacy in patients undergoing treatment with immune checkpoint inhibitors (ICIs), but the results remain controversial. Methods Under the guidance of a...

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Bibliographic Details
Main Authors: Xiaoxiang Zhou, Zhuoran Yao, Huaxia Yang, Naixin Liang, Xuan Zhang, Fengchun Zhang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12916-020-01549-2