Optical triggered seizures using a caged 4-Aminopyridine

Optical triggered seizures using a caged 4-Aminopyridine

Animal models of epilepsy are critical not only for understanding the fundamental mechanism of epilepsy but also for testing the efficacy of new antiepileptic drugs and novel therapeutic interventions. Photorelease of caged molecules is widely used in biological research to control pharmacologic eve...

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Bibliographic Details
Main Authors: Mingrui eZhao, Laura M. McGarry, Hongtao eMa, Sam eHarris, Jason eBerwick, Rafael eYuste, Theodore eSchwartz
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Neuroscience
Subjects:
Electrophysiology
Neocortex
optical imaging
photostimulation
epilepsy model
caged chemical
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00025/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00025/full

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