Optical triggered seizures using a caged 4-Aminopyridine
Animal models of epilepsy are critical not only for understanding the fundamental mechanism of epilepsy but also for testing the efficacy of new antiepileptic drugs and novel therapeutic interventions. Photorelease of caged molecules is widely used in biological research to control pharmacologic eve...
Main Authors: | Mingrui eZhao, Laura M. McGarry, Hongtao eMa, Sam eHarris, Jason eBerwick, Rafael eYuste, Theodore eSchwartz |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-02-01
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Series: | Frontiers in Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00025/full |
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