Comparative analysis of age in monocrotaline-induced pulmonary hypertensive rats

Comparative analysis of age in monocrotaline-induced pulmonary hypertensive rats

Pulmonary arterial hypertension (PAH) is a rare, progressive, and fatal cardiovascular/lung disease. The incidence rate is affected by age. Monocrotaline (MCT, 60 mg/kg)-treated rats are widely used as an experimental PAH model. Here, we found that young rats died at a mean of 23.4 days after MCT in...

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Bibliographic Details
Main Authors: Akiko Kawade, Aya Yamamura, Moe Fujiwara, Saki Kobayashi, Shiho Mori, Chihiro Horii, Akari Hiraku, Sayo Suzumura, Kikuo Tsukamoto, Naoki Ohara, Rubii Kondo, Yoshiaki Suzuki, Hisao Yamamura
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Journal of Pharmacological Sciences
Subjects:
Pulmonary hypertension
Monocrotaline
Age
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000542

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http://www.sciencedirect.com/science/article/pii/S1347861321000542

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