Model-selection-based approach for calculating cellular multiplicity of infection during virus colonization of multi-cellular hosts.

The cellular multiplicity of infection (MOI) is a key parameter for describing the interactions between virions and cells, predicting the dynamics of mixed-genotype infections, and understanding virus evolution. Two recent studies have reported in vivo MOI estimates for Tobacco mosaic virus (TMV) an...

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Bibliographic Details
Main Authors: Mark P Zwart, Nicolas Tromas, Santiago F Elena
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3665715?pdf=render