6,6′-Dihydroxythiobinupharidine (DTBN) Purified from <i>Nuphar lutea</i> Leaves Is an Inhibitor of Protein Kinase C Catalytic Activity

6,6′-Dihydroxythiobinupharidine (DTBN) Purified from <i>Nuphar lutea</i> Leaves Is an Inhibitor of Protein Kinase C Catalytic Activity

Water lily (<i>Nuphar)</i> bioactive extracts have been widely used in traditional medicine owing to their multiple applications against human ailments. Phyto-active <i>Nuphar</i> extracts and their purified and synthetic derivatives have attracted the attention of ethnobotan...

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Bibliographic Details
Main Authors: Kamran Waidha, Nikhil Ponnoor Anto, Divya Ram Jayaram, Avi Golan-Goldhirsh, Saravanakumar Rajendran, Etta Livneh, Jacob Gopas
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
protein kinase C (PKC)
<i>Nuphar lutea</i>
6,6′-dihydroxythiobinupharidine (DTBN)
kinase inhibitor
Ramachandran plot
homology docking modeling
Online Access:https://www.mdpi.com/1420-3049/26/9/2785

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https://www.mdpi.com/1420-3049/26/9/2785

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