The Protective Effects of the Autophagic and Lysosomal Machinery in Vascular and Valvular Calcification: A Systematic Review

The Protective Effects of the Autophagic and Lysosomal Machinery in Vascular and Valvular Calcification: A Systematic Review

Background: Autophagy is a highly conserved catabolic homeostatic process, crucial for cell survival. It has been shown that autophagy can modulate different cardiovascular pathologies, including vascular calcification (VCN). Objective: To assess how modulation of autophagy, either through induction...

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Bibliographic Details
Main Authors: Cédric H. G. Neutel, Jhana O. Hendrickx, Wim Martinet, Guido R. Y. De Meyer, Pieter-Jan Guns
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
vascular calcification
aortic valve calcification
autophagy
lysosomes
vascular smooth muscle cell (VSMC)
valvular interstitial cell (VIC)
Online Access:https://www.mdpi.com/1422-0067/21/23/8933

Internet

https://www.mdpi.com/1422-0067/21/23/8933

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