VCAM-1 and VLA-4 modulate dendritic cell IL-12p40 production in experimental visceral leishmaniasis.

VCAM-1 and VLA-4 modulate dendritic cell IL-12p40 production in experimental visceral leishmaniasis.

Vascular cell adhesion molecule-1 (VCAM-1) interacts with its major ligand very late antigen-4 (VLA-4) to mediate cell adhesion and transendothelial migration of leukocytes. We report an important role for VCAM-1/VLA-4 interactions in the generation of immune responses during experimental visceral l...

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Bibliographic Details
Main Authors: Amanda C Stanley, Jane E Dalton, Susanna H Rossotti, Kelli P MacDonald, Yonghong Zhou, Fabian Rivera, Wayne A Schroder, Asher Maroof, Geoff R Hill, Paul M Kaye, Christian R Engwerda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2528938?pdf=render

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http://europepmc.org/articles/PMC2528938?pdf=render

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