Impact of Sleep–Wake-Associated Neuromodulators and Repetitive Low-Frequency Stimulation on Human iPSC-Derived Neurons

Impact of Sleep–Wake-Associated Neuromodulators and Repetitive Low-Frequency Stimulation on Human iPSC-Derived Neurons

The cross-regional neurons in the brainstem, hypothalamus, and thalamus regulate the central nervous system, including the cerebral cortex, in a sleep–wake cycle-dependent manner. A characteristic brain wave, called slow wave, of about 1 Hz is observed during non-REM sleep, and the sleep homeostasis...

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Bibliographic Details
Main Authors: Remi Yokoi, Miho Okabe, Naoki Matsuda, Aoi Odawara, Akihiro Karashima, Ikuro Suzuki
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Neuroscience
Subjects:
human iPSC-derived neuron
micro-electrode array
circadian rhythms
neurotransmitters
low-frequency stimulation
wake
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00554/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.00554/full

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