Detection of Genetic Variations in Coagulopathy-Related Genes Using Ramified Rolling Circle Amplification

We evaluated single nucleotide polymorphism (SNP) detection via a target-capture, C-probe ligation, and RAM assay in a single-blind comparison to clinical samples that had been tested with FDA-cleared tests for up to 4 different vascular disease-related SNPs. In the RAM assay circulizable linear pro...

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Bibliographic Details
Main Authors: James H. Smith, Miao Cui, David Y. Zhang, Thomas P. Beals, Fei Ye
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/641090