Macrophages and Their Role in Atherosclerosis: Pathophysiology and Transcriptome Analysis

Atherosclerosis can be regarded as a chronic inflammatory state, in which macrophages play different and important roles. Phagocytic proinflammatory cells populate growing atherosclerotic lesions, where they actively participate in cholesterol accumulation. Moreover, macrophages promote formation of...

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Bibliographic Details
Main Authors: Yuri V. Bobryshev, Ekaterina A. Ivanova, Dimitry A. Chistiakov, Nikita G. Nikiforov, Alexander N. Orekhov
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2016/9582430