IGF-1 enhances BMSC viability, migration, and anti-apoptosis in myocardial infarction via secreted frizzled-related protein 2 pathway

IGF-1 enhances BMSC viability, migration, and anti-apoptosis in myocardial infarction via secreted frizzled-related protein 2 pathway

Abstract Background Bone marrow mesenchymal stem cell (BMSC) transplantation represents a promising therapeutic strategy for ischemic heart disease. However, its effects are hampered by the poor viability of transplanted cells and the hostile microenvironment of the ischemic region. Insulin-like gro...

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Bibliographic Details
Main Authors: Mingzhuo Lin, Xinyue Liu, Haoxiao Zheng, Xiaohui Huang, Yu Wu, Anqing Huang, Hailan Zhu, Yunzhao Hu, Weiyi Mai, Yuli Huang
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Stem Cell Research & Therapy
Subjects:
Bone marrow mesenchymal stem cell
Insulin-like growth factor-1
Myocardial infarction
Secreted frizzled-related protein 2
Online Access:https://doi.org/10.1186/s13287-019-1544-y

Internet

https://doi.org/10.1186/s13287-019-1544-y

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