microRNAs regulate cell-to-cell variability of endogenous target gene expression in developing mouse thymocytes.

The development and homeostasis of multicellular organisms relies on gene regulation within individual constituent cells. Gene regulatory circuits that increase the robustness of gene expression frequently incorporate microRNAs as post-transcriptional regulators. Computational approaches, synthetic...

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Bibliographic Details
Main Authors: Rory Blevins, Ludovica Bruno, Thomas Carroll, James Elliott, Antoine Marcais, Christina Loh, Arnulf Hertweck, Azra Krek, Nikolaus Rajewsky, Chang-Zheng Chen, Amanda G Fisher, Matthias Merkenschlager
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4340958?pdf=render