POLE2 knockdown reduce tumorigenesis in esophageal squamous cells

POLE2 knockdown reduce tumorigenesis in esophageal squamous cells

Abstract Background Esophageal squamous cell carcinoma (ESCC) is one of the most frequent malignant tumors originated from digestive system around the world and the treatment was limited by the unclear mechanism. DNA polymerase epsilon 2, accessory subunit (POLE2) is involved in DNA replication, rep...

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Bibliographic Details
Main Authors: Yongjun Zhu, Gang Chen, Yang Song, Zhiming Chen, Xiaofeng Chen
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Cancer Cell International
Subjects:
ESCC
POLE2
Cell proliferation
Cell apoptosis
Cell migration
Online Access:http://link.springer.com/article/10.1186/s12935-020-01477-4

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http://link.springer.com/article/10.1186/s12935-020-01477-4

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