The clinical spectrum and immunopathological mechanisms underlying ZIKV-induced neurological manifestations

Since the 2015 to 2016 outbreak in America, Zika virus (ZIKV) infected almost 900,000 patients. This international public health emergency was mainly associated with a significant increase in the number of newborns with congenital microcephaly and abnormal neurologic development, known as congenital...

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Main Authors: Igor Salerno Filgueiras, Amanda Torrentes de Carvalho, Daniela Prado Cunha, Dennyson Leandro Mathias da Fonseca, Nadia El Khawanky, Paula Paccielli Freire, Gustavo Cabral-Miranda, Lena F. Schimke, Niels Olsen Saraiva Camara, Hans D. Ochs, Jean Pierre Schatzmann Peron, Otávio Cabral-Marques, Zilton Farias Meira de Vasconcelos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341629/?tool=EBI