From pairs of most similar sequences to phylogenetic best matches
Abstract Background Many of the commonly used methods for orthology detection start from mutually most similar pairs of genes (reciprocal best hits) as an approximation for evolutionary most closely related pairs of genes (reciprocal best matches). This approximation of best matches by best hits bec...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | Algorithms for Molecular Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13015-020-00165-2 |