From pairs of most similar sequences to phylogenetic best matches

Abstract Background Many of the commonly used methods for orthology detection start from mutually most similar pairs of genes (reciprocal best hits) as an approximation for evolutionary most closely related pairs of genes (reciprocal best matches). This approximation of best matches by best hits bec...

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Bibliographic Details
Main Authors: Peter F. Stadler, Manuela Geiß, David Schaller, Alitzel López Sánchez, Marcos González Laffitte, Dulce I. Valdivia, Marc Hellmuth, Maribel Hernández Rosales
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Algorithms for Molecular Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13015-020-00165-2