The granuloma in tuberculosis: Dynamics of a host-pathogen collusion

A granuloma is defined as an inflammatory mononuclear cell infiltrate that, while capable of limiting growth of Mycobacterium tuberculosis, also provides a survival niche from which the bacteria may disseminate. The tuberculosis lesion is highly dynamic and shaped by both, immune response elements a...

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Bibliographic Details
Main Authors: Stefan eEhlers, Ulrich E Schaible
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00411/full