Morphine biotransformation genes and neonatal clinical factors predicted behaviour problems in very preterm children at 18 monthsResearch in context

Background: Behaviour problems are prevalent among children born very preterm (≤ 32 weeks gestation), and have been associated with morphine exposure. Morphine accumulation in the brain is determined by genetic variations related to morphine biotransformation. The objective of the study was to inves...

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Bibliographic Details
Main Authors: Cecil M.Y. Chau, Colin J.D. Ross, Vann Chau, Anne R. Synnes, Steven P. Miller, Bruce Carleton, Ruth E. Grunau
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419300490