The Clinical Utility of Optical Genome Mapping for the Assessment of Genomic Aberrations in Acute Lymphoblastic Leukemia

The Clinical Utility of Optical Genome Mapping for the Assessment of Genomic Aberrations in Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) is the most prevalent type of cancer occurring in children. ALL is characterized by structural and numeric genomic aberrations that strongly correlate with prognosis and clinical outcome. Usually, a combination of cyto- and molecular genetic methods (karyotyping, a...

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Bibliographic Details
Main Authors: Jonathan Lukas Lühmann, Marie Stelter, Marie Wolter, Josephine Kater, Jana Lentes, Anke Katharina Bergmann, Maximilian Schieck, Gudrun Göhring, Anja Möricke, Gunnar Cario, Markéta Žaliová, Martin Schrappe, Brigitte Schlegelberger, Martin Stanulla, Doris Steinemann
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
ALL
Optical Genome Mapping
molecular karyotyping
prognostic marker
risk assessment
gene fusion
Online Access:https://www.mdpi.com/2072-6694/13/17/4388

Internet

https://www.mdpi.com/2072-6694/13/17/4388

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