Vaginal challenge with an SIV-based dual reporter system reveals that infection can occur throughout the upper and lower female reproductive tract.

Vaginal challenge with an SIV-based dual reporter system reveals that infection can occur throughout the upper and lower female reproductive tract.

The majority of new HIV infections occur in women as a result of heterosexual intercourse, overcoming multiple innate barriers to infection within the mucosa. However, the avenues through which infection is established, and the nature of bottlenecks to transmission, have been the source of considera...

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Bibliographic Details
Main Authors: Daniel J Stieh, Danijela Maric, Z L Kelley, Meegan R Anderson, Holly Z Hattaway, Beth A Beilfuss, Katharina B Rothwangl, Ronald S Veazey, Thomas J Hope
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4192600?pdf=render

Internet

http://europepmc.org/articles/PMC4192600?pdf=render

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