DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma.

<h4>Background</h4>Aberrant DNA methylation is common in lung adenocarcinoma, but its timing in the phases of tumor development is largely unknown. Delineating when abnormal DNA methylation arises may provide insight into the natural history of lung adenocarcinoma and the role that DNA m...

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Bibliographic Details
Main Authors: Suhaida A Selamat, Janice S Galler, Amit D Joshi, M Nicky Fyfe, Mihaela Campan, Kimberly D Siegmund, Keith M Kerr, Ite A Laird-Offringa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21731750/?tool=EBI