Assessing stationary distributions derived from chromatin contact maps

Abstract Background The spatial configuration of chromosomes is essential to various cellular processes, notably gene regulation, while architecture related alterations, such as translocations and gene fusions, are often cancer drivers. Thus, eliciting chromatin conformation is important, yet challe...

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Bibliographic Details
Main Authors: Mark R. Segal, Kipper Fletez-Brant
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-3424-y