Assessing stationary distributions derived from chromatin contact maps
Abstract Background The spatial configuration of chromosomes is essential to various cellular processes, notably gene regulation, while architecture related alterations, such as translocations and gene fusions, are often cancer drivers. Thus, eliciting chromatin conformation is important, yet challe...
Main Authors: | Mark R. Segal, Kipper Fletez-Brant |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-02-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-020-3424-y |
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