Impaired Mitochondrial and Metabolic Function of Fibroblasts Derived from Patients with Recessive Dystrophic and Junctional Epidermolysis Bullosa

Impaired Mitochondrial and Metabolic Function of Fibroblasts Derived from Patients with Recessive Dystrophic and Junctional Epidermolysis Bullosa

Background: Recessive dystrophic epidermolysis bullosa (RDEB) and junctional EB (JEB) are inherited disorders characterised by fragility and blistering of epithelial tissues leading to pain, pruritus, and adherent scarring. The severity and chronic nature of the resultant skin wounds significantly r...

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Bibliographic Details
Main Authors: Ilona Tietzová, Kirk Twaroski, Cindy Eide, Julie H. Ostrander, Peter A. Crawford, Jakub Tolar
Format: Article
Language:English
Published: European Medical Journal 2020-12-01
Series:European Medical Journal Dermatology
Subjects:
cellular bioenergetics
fibroblasts
fractal dimension
mitochondria
epidermolysis bullosa
Online Access:https://www.emjreviews.com/dermatology/article/impaired-mitochondrial-and-metabolic-function-of-fibroblasts-derived-from-patients-with-recessive-dystrophic-and-junctional-epidermolysis-bullosa/

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https://www.emjreviews.com/dermatology/article/impaired-mitochondrial-and-metabolic-function-of-fibroblasts-derived-from-patients-with-recessive-dystrophic-and-junctional-epidermolysis-bullosa/

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