Synergetic Effect of rHDL and LXR Agonist on Reduction of Atherosclerosis in Mice

High-density lipoproteins (HDLs) are unique in that they play an important role in the reverse cholesterol transport process. However, reconstituted HDL (rHDL) infusions have demonstrated limited beneficial effect in clinical practice. This is perhaps a consequence of the limited cholesterol efflux...

Full description

Bibliographic Details
Main Authors: Emily E. Morin, Yanhong Guo, Hongliang He, Wenmin Yuan, Whitney N. Souery, Maria V. Fawaz, Yuqing Eugene Chen, Anna Schwendeman
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.513031/full