Hematopoietic stem/progenitor cell proliferation and differentiation is differentially regulated by high-density and low-density lipoproteins in mice.

<h4>Rationale</h4>Hematopoietic stem/progenitor cells (HSPC) are responsible for maintaining the blood system as a result of their self-renewal and multilineage differentiation capacity. Recently, studies have suggested that HDL cholesterol may inhibit and impaired cholesterol efflux may...

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Bibliographic Details
Main Authors: Yingmei Feng, Sarah Schouteden, Rachel Geenens, Vik Van Duppen, Paul Herijgers, Paul Holvoet, Paul P Van Veldhoven, Catherine M Verfaillie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23144813/?tool=EBI