Elastin-Like Recombinamer Hydrogels for Improved Skeletal Muscle Healing Through Modulation of Macrophage Polarization

Elastin-Like Recombinamer Hydrogels for Improved Skeletal Muscle Healing Through Modulation of Macrophage Polarization

Large skeletal muscle injuries, such as a volumetric muscle loss (VML), often result in an incomplete regeneration due to the formation of a non-contractile fibrotic scar tissue. This is, in part, due to the outbreak of an inflammatory response, which is not resolved over time, meaning that type-1 m...

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Bibliographic Details
Main Authors: Arturo Ibáñez-Fonseca, Silvia Santiago Maniega, Darya Gorbenko del Blanco, Benedicta Catalán Bernardos, Aurelio Vega Castrillo, Ángel José Álvarez Barcia, Matilde Alonso, Héctor J. Aguado, José Carlos Rodríguez-Cabello
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
skeletal muscle healing
volumetric muscle loss
biomaterials
elastin-like recombinamers
hydrogels
macrophage polarization
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00413/full

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https://www.frontiersin.org/article/10.3389/fbioe.2020.00413/full

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