Dissecting the Contribution of Release Factor Interactions to Amber Stop Codon Reassignment Efficiencies of the <i>Methanocaldococcus jannaschii</i> Orthogonal Pair

Dissecting the Contribution of Release Factor Interactions to Amber Stop Codon Reassignment Efficiencies of the <i>Methanocaldococcus jannaschii</i> Orthogonal Pair

Non-canonical amino acids (ncAAs) are finding increasing use in basic biochemical studies and biomedical applications. The efficiency of ncAA incorporation is highly variable, as a result of competing system composition and codon context effects. The relative quantitative contribution of the multipl...

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Bibliographic Details
Main Authors: David G. Schwark, Margaret A. Schmitt, John D. Fisk
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Genes
Subjects:
genetic code expansion
release factor 1
amber stop codon suppression
<i>M. jannaschii</i> orthogonal pair
fluorescence-based screen
Online Access:https://www.mdpi.com/2073-4425/9/11/546

Internet

https://www.mdpi.com/2073-4425/9/11/546

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