SALL4 as a transcriptional and epigenetic regulator in normal and leukemic hematopoiesis

SALL4 as a transcriptional and epigenetic regulator in normal and leukemic hematopoiesis

Abstract In recent years, there has been substantial progress in our knowledge of the molecular pathways by which stem cell factor SALL4 regulates the embryonic stem cell (ESC) properties, developmental events, and human cancers. This review summarizes recent advances in the biology of SALL4 with a...

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Bibliographic Details
Main Author: Jianchang Yang
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Biomarker Research
Subjects:
Pluripotency
Hematopoietic stem and progenitor cells
Apoptosis
Transgenic
Wnt/β-catenin signaling
Mixed-lineage leukemia
Online Access:http://link.springer.com/article/10.1186/s40364-017-0115-6

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http://link.springer.com/article/10.1186/s40364-017-0115-6

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