Molecular determinants of large cargo transport into the nucleus

Molecular determinants of large cargo transport into the nucleus

Nucleocytoplasmic transport is tightly regulated by the nuclear pore complex (NPC). Among the thousands of molecules that cross the NPC, even very large (>15 nm) cargoes such as pathogens, mRNAs and pre-ribosomes can pass the NPC intact. For these cargoes, there is little quantitative underst...

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Bibliographic Details
Main Authors: Giulia Paci, Tiantian Zheng, Joana Caria, Anton Zilman, Edward A Lemke
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-07-01
Series:eLife
Subjects:
nuclear transport
permeabilized cells
large cargo
import kinetics
NLS
capsid
Online Access:https://elifesciences.org/articles/55963

Internet

https://elifesciences.org/articles/55963

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