Random or stochastic monoallelic expressed genes are enriched for neurodevelopmental disorder candidate genes.

Random or stochastic monoallelic expressed genes (StMA genes) represent a unique form of monoallelic expression where allelic choice is made at random early in development. The consequential clonal diversity provides opportunity for functional heterozygosity in tissues such as the brain, and can imp...

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Bibliographic Details
Main Authors: Aaron R Jeffries, David A Collier, Evangelos Vassos, Sarah Curran, Caroline M Ogilvie, Jack Price
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24386451/pdf/?tool=EBI