LTR-retrotransposon transcriptome modulation in response to endotoxin-induced stress in PBMCs

LTR-retrotransposon transcriptome modulation in response to endotoxin-induced stress in PBMCs

Abstract Background Human Endogenous Retroviruses (HERVs) and Mammalian apparent LTR-retrotransposons (MaLRs) represent the 8% of our genome and are distributed among our 46 chromosomes. These LTR-retrotransposons are thought to be essentially silent except in cancer, autoimmunity and placental deve...

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Main Authors: Marine Mommert, Olivier Tabone, Guy Oriol, Elisabeth Cerrato, Audrey Guichard, Magali Naville, Paola Fournier, Jean-Nicolas Volff, Alexandre Pachot, Guillaume Monneret, Fabienne Venet, Karen Brengel-Pesce, Julien Textoris, François Mallet
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Genomics
Subjects:
HERV transcriptome
PBMCs
LPS
Endotoxin tolerance
Signalling pathways
Sepsis
Online Access:http://link.springer.com/article/10.1186/s12864-018-4901-9

Internet

http://link.springer.com/article/10.1186/s12864-018-4901-9

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