Trafficking of glycosylphosphatidylinositol anchored proteins from the endoplasmic reticulum to the cell surface

In eukaryotes, many cell surface proteins are attached to the plasma membrane via a glycolipid glycosylphosphatidylinositol (GPI) anchor. GPI-anchored proteins (GPI-APs) receive the GPI anchor as a conserved posttranslational modification in the lumen of the endoplasmic reticulum (ER). After anchor...

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Bibliographic Details
Main Authors: Manuel Muñiz, Howard Riezman
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520354341