Cancer Testis Antigens and Immunotherapy: Expression of PRAME Is Associated with Prognosis in Soft Tissue Sarcoma

Cancer Testis Antigens and Immunotherapy: Expression of PRAME Is Associated with Prognosis in Soft Tissue Sarcoma

(1) Background: PRAME, NY-ESO-1, and SSX2 are cancer testis antigens (CTAs), which are expressed in testicular germ cells with re-expression in numerous cancer types. Their ability to elicit humoral and cellular immune responses have rendered them promising targets for cancer immunotherapy, but they...

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Bibliographic Details
Main Authors: Markus Albertsmeier, Annelore Altendorf-Hofmann, Lars H. Lindner, Rolf D. Issels, Eric Kampmann, Hans-Roland Dürr, Gabriele Schubert-Fritschle, Martin K. Angele, Thomas Kirchner, Achim A. Jungbluth, Thomas Knösel
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
soft tissue sarcoma
human
cancer/testis antigens
PRAME
NY-ESO-1
SSX2
Online Access:https://www.mdpi.com/2072-6694/12/12/3612

Internet

https://www.mdpi.com/2072-6694/12/12/3612

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