A Bistable Switch in Virus Dynamics Can Explain the Differences in Disease Outcome Following SIV Infections in Rhesus Macaques

A Bistable Switch in Virus Dynamics Can Explain the Differences in Disease Outcome Following SIV Infections in Rhesus Macaques

Experimental studies have shown that the size and infectious-stage of viral inoculum influence disease outcomes in rhesus macaques infected with simian immunodeficiency virus. The possible contribution to disease outcome of antibody developed after transmission and/or present in the inoculum in free...

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Bibliographic Details
Main Authors: Stanca M. Ciupe, Christopher J. Miller, Jonathan E. Forde
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
SIV
immune complexes
mathematical model
bistable dynamics
stochastic model
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01216/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01216/full

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