Synthesis and Anti-Hepatocarcinoma Effect of Amino Acid Derivatives of Pyxinol and Ocotillol

Aiming at seeking an effective anti-hepatocarcinoma drug with low toxicity, a total of 24 amino acid derivatives (20 new along with 4 known derivatives) of two active ocotillol-type sapogenins (pyxinol and ocotillol) were synthesized. Both in vitro and in vivo anti-hepatocarcinoma effects of derivat...

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Bibliographic Details
Main Authors: Ying Zhang, Hui Yu, Shuzheng Fu, Luying Tan, Junli Liu, Baisong Zhou, Le Li, Yunhe Liu, Caixia Wang, Pingya Li, Jinping Liu
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/4/780