Characterization of slow cycling corneal limbal epithelial cells identifies putative stem cell markers

Abstract In order to identify reliable markers of corneal epithelial stem cells, we employed an inducible transgenic “pulse-chase” murine model (K5Tta × TRE-H2BGFP) to localize, purify, and characterize slow cycling cells in the cornea. The retention of GFP labeling in slowly dividing cells allowed...

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Bibliographic Details
Main Authors: R. Sartaj, C. Zhang, P. Wan, Z. Pasha, V. Guaiquil, A. Liu, J. Liu, Y. Luo, E. Fuchs, M. I. Rosenblatt
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04006-y