B7-H1-deficiency enhances the potential of tolerogenic dendritic cells by activating CD1d-restricted type II NKT cells.

<h4>Background</h4>Dendritic cells (DC) can act tolerogenic at a semi-mature stage by induction of protective CD4(+) T cell and NKT cell responses.<h4>Methodology/principal findings</h4>Here we studied the role of the co-inhibitory molecule B7-H1 (PD-L1, CD274) on semi-mature...

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Bibliographic Details
Main Authors: Carolin Brandl, Sonja Ortler, Thomas Herrmann, Susanna Cardell, Manfred B Lutz, Heinz Wiendl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20520738/pdf/?tool=EBI