ZBED6 regulates Igf2 expression partially through its regulation of miR483 expression

Abstract The expression of Igf2 in mammals shows a complex regulation involving multiple promoters and epigenetic mechanisms. We previously identified a novel regulatory mechanism based on the interaction between the transcriptional factor ZBED6 and Igf2 intron. Disruption of the ZBED6-Igf2 interact...

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Bibliographic Details
Main Authors: Rakan Naboulsi, Mårten Larsson, Leif Andersson, Shady Younis
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98777-0