Leukocyte Integrin Antagonists as a Novel Option to Treat Dry Age-Related Macular Degeneration

Leukocyte Integrin Antagonists as a Novel Option to Treat Dry Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a complex multifactorial degenerative disease that leads to irreversible blindness. AMD affects the macula, the central part of the retina responsible for sharp central vision. Retinal pigment epithelium (RPE) is the main cellular type affected in dry AMD. R...

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Bibliographic Details
Main Authors: Monica Baiula, Alberto Caligiana, Andrea Bedini, Junwei Zhao, Federica Santino, Martina Cirillo, Luca Gentilucci, Daria Giacomini, Santi Spampinato
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
age-related macular degeneration
retinal pigment epithelium cells
leukocyte integrins
inflammation
integrin antagonist
immune cells
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.617836/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.617836/full

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