MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network

MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network

MiR-34a was demonstrated to be upregulated during the osteogenic differentiation of human adipose-derived stem cells (hASCs). Overexpression of miR-34a significantly increased alkaline phosphatase activity, mineralization capacity, and the expression of osteogenesis-associated genes in hASCs in vitr...

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Bibliographic Details
Main Authors: Cong Fan, Lingfei Jia, Yunfei Zheng, Chanyuan Jin, Yunsong Liu, Hao Liu, Yongsheng Zhou
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671116301023

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http://www.sciencedirect.com/science/article/pii/S2213671116301023

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