Intrahepatic TH17/TReg Cells in Homeostasis and Disease—It’s All About the Balance

Both acute and chronic hepatic inflammation likely result from an imbalance in the TH1/TH2 cell response and can lead to liver fibrosis and end-stage liver disease. More recently, a novel CD4+ T helper cell subset was described, characterized by the production of IL-17 and IL-22. These TH17 cells 50...

Full description

Bibliographic Details
Main Authors: Hannah K. Drescher, Lea M. Bartsch, Sabine Weiskirchen, Ralf Weiskirchen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.588436/full