Impact of insulin on primary arcuate neurons culture is dependent on early-postnatal nutritional status and neuronal subpopulation.

Impact of insulin on primary arcuate neurons culture is dependent on early-postnatal nutritional status and neuronal subpopulation.

Nutrition plays a critical role in programming and shaping linear growth during early postnatal life through direct action on the development of the neuroendocrine somatotropic (GH/IGF-1) axis. IGF-1 is a key factor in modulating the programming of linear growth during this period. Notably, IGF-1 pr...

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Bibliographic Details
Main Authors: Lyvianne Decourtye, Maud Clemessy, Erik Mire, Tatiana Ledent, Laurence Périn, Iain C Robinson, Yves Le Bouc, Laurent Kappeler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5821369?pdf=render

Internet

http://europepmc.org/articles/PMC5821369?pdf=render

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