The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma

The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma

The active form of vitamin B6, pyridoxal phosphate (PLP), is essential for human metabolism. The brain is dependent on vitamin B6 for its neurotransmitter balance. To obtain insight into the genetic determinants of vitamin B6 homeostasis, we conducted a genome-wide association study (GWAS) of the B6...

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Bibliographic Details
Main Authors: Loes M. Loohuis, Monique Albersen, Simone de Jong, Timothy Wu, Jurjen J. Luykx, Judith J. M. Jans, Nanda M. Verhoeven-Duif, Roel A. Ophoff
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Genes
Subjects:
genome wide association study
vitamin B6
cerebrospinal fluid
plasma
Online Access:http://www.mdpi.com/2073-4425/10/1/8

Internet

http://www.mdpi.com/2073-4425/10/1/8

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