Innate Response Activator (IRA) B Cells Reside in Human Tonsils and Internalize Bacteria In Vitro.

Innate response activator (IRA) B cells have been described in mice as a subset of B-1a B cells that produce granulocyte/macrophage colony-stimulating factor (GM-CSF) and have been found in the spleen upon activation. In humans, identification, tissue localization and functionality of these lymphocy...

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Main Authors: Nico Chiappini, Rocco Cantisani, Laura Pancotto, Paolo Ruggiero, Domenico Rosa, Andrea Manetti, Antonio Romano, Francesca Montagnani, Sylvie Bertholet, Flora Castellino, Giuseppe Del Giudice
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4466315?pdf=render