Chronic delivery of antibody fragments using immunoisolated cell implants as a passive vaccination tool.

Chronic delivery of antibody fragments using immunoisolated cell implants as a passive vaccination tool.

BACKGROUND: Monoclonal antibodies and antibody fragments are powerful biotherapeutics for various debilitating diseases. However, high production costs, functional limitations such as inadequate pharmacokinetics and tissue accessibility are the current principal disadvantages for broadening their us...

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Main Authors: Osiris Marroquin Belaunzaran, Maria Isabel Cordero, Veronica Setola, Siro Bianchi, Carmela Galli, Nicolas Bouche, Vladimir Mlynarik, Rolf Gruetter, Carmen Sandi, Jean-Charles Bensadoun, Maurizio Molinari, Patrick Aebischer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3080361?pdf=render

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http://europepmc.org/articles/PMC3080361?pdf=render

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